Immunohistochemistry Antibody
Immunohistochemistry (IHC) is a powerful laboratory technique that uses antibodies to detect specific antigens (proteins) in tissue sections. By exploiting the principle of antibodies binding specifically to antigens in biological tissues, IHC allows scientists and pathologists to visualize the distribution and localization of specific cellular components under a microscope. This is achieved by labeling the antibody with a marker, such as a fluorescent dye or an enzyme that produces a color change.
The choice of antibody is critical to the success of the procedure. Monoclonal antibodies offer high specificity for a single epitope, while polyclonal antibodies can recognize multiple epitopes on the same antigen. In clinical diagnostics, IHC antibodies are indispensable for identifying different types of cancer. For instance, testing for HER2 or estrogen receptors in breast cancer tissue helps oncologists determine the most effective targeted therapy for a patient.
Beyond diagnostics, IHC is a cornerstone of biomedical research. It…



